The dish was created in the United States in the 1930s. The name “meatloaf” comes from its shape, which resembles a loaf of bread.
Making meatloaf is a popular dish for many families. It can be prepared in less than 30 minutes and contains a variety of ingredients that can be customized to the family’s tastes. All you need is ground beef, eggs, bread crumbs, onion, garlic, salt, and pepper.
Most of us know how to prepare meatloaf, but we might stop and think: how long to cook meatloaf at 375? Don’t worry, I have all the info you might need right here.
How Long To Cook Meatloaf At 375?

You can cook your meatloaf at the temperature of 375 degrees Fahrenheit between 25 min to 2 hours, depending on the size of the meatloaf. A medium sized-meatloaf will need around 1 hour to cook at 375 degrees.
The cooking time for meatloaf varies depending on the size of the meatloaf and the temperature you cook it at. A small meatloaf will need half an hour to bake at 375, and a bigger meatloaf will need between one hour to two hours to cook at the same temp.
The best way to figure out how long to cook your meatloaf is to use a meat thermometer, which will ensure that your meatloaf is cooked evenly.
The cooking time for meatloaf is usually between 45 minutes to an hour. The cooking time for meatloaf varies depending on the size of the loaf and the temperature.
The oven should be preheated to 375 degrees Fahrenheit, and the meatloaf pan should be greased with butter before adding the meatloaf.
Cooking temperature is one of the most important factors in determining how long it will take to cook a meatloaf. The cooking time is also determined by the size of the loaf, how much fat is in the meat, and its shape.
The oven temperature should be set at 375 degrees Fahrenheit, and it should be preheated for 20 minutes before adding the meatloaf. A good rule of thumb is to cook a 1-pound loaf for 45 minutes to an hour.
How Long To Cook 1 Lb Meatloaf At 375?
The cooking time for 1 lb meatloaf at 375 degrees Fahrenheit is between 25 to 30 minutes, or just half an hour. The cooking time will depend on how thick the meatloaf is.
The best method is slow cooking. Slow cooking is a popular method of cooking that can be done in a crock pot, slow cooker, Dutch oven, or other heavy pot with a cover.
The meatloaf will cook more quickly if it is made from leaner ground beef, but this will also result in a drier meatloaf. You can create the same flavor profile while using less lean beef by adding liquid like tomato sauce or ketchup.
How Long To Cook 2 Lb Meatloaf At 375?

You will have to cook a 2 lb meatloaf for between 40 and 50 minutes at 375 degrees Fahrenheit.
Cooking meatloaf can be a daunting task. There are many factors that can affect the cooking process, such as the cooking temperature, the type of pan used, and the size of the meatloaf.
The most important factor to consider is how long to cook meatloaf at 375. This is because it will determine how well done the meatloaf will be when it’s finished.
For example, if you cook your 2 lb meatloaf at 375 for 35 minutes, then you will have a medium rare cooked meatloaf. If you cook it for 20 minutes, then you will have a well-done cooked 2 lb meatloaf.
How Long To Cook 3 Lb Meatloaf At 375?
Cook a medium meatloaf or 3 lb meatloaf for 1 hour at 375 degrees Fahrenheit. The best way to find out how long to cook 3 lb meatloaf at 375 degrees is to follow a meatloaf recipe.
The cooking time will depend on the size of the meatloaf. One rule of thumb is that a 3 lb meatloaf will take about one hour to cook through when baking at 375 degrees Fahrenheit.
This is the average time it takes to cook meatloaf. It can take longer if you are cooking a larger batch or if your oven doesn’t heat up as well as it should.
How Long To Cook 4 Lb Meatloaf At 375?

The length of time it takes to cook a meatloaf varies depending on the size and shape. A 4-pound loaf will take approximately 1 hour and a half to cook at 375 degrees Fahrenheit.
Meatloaf is a dish that can be made from many different types of meats, but traditionally it is a mixture of ground beef and pork. The meatloaf is then shaped into a loaf and cooked in the oven or on the stovetop.
There are many different ways to cook a meatloaf, but it usually takes about an hour at 375 degrees Fahrenheit. That goes for a medium-sized meatloaf, but a bigger one, like this one, will take a bit longer.
How Long To Cook 5 Lb Meatloaf At 375?
Now, this is a big meatloaf, which can take up to two hours to bake at 375 degrees Fahrenheit. Of course, there are many factors that come into play, such as the size of the meatloaf, the type of oven, and the type of pan.
A recipe will give an estimate for a specific set of ingredients and instructions, as well as the size of the loaf pan, how you preheat the baking dish and oven, and other ingredients since this is a higher temperature and bigger meatloaf.
So, how long to cook meatloaf at 375? The recommended prep time is up to 2 hours if baking a big meatloaf, but all the smaller options will be done quickly.
How Long Do You Cook Meatloaf For? (Other Temperatures)

The cooking time for meatloaf varies depending on the type of meat, the size of the loaf, and how you like your meatloaf cooked.
Depending on the size of your meatloaf, it can take anywhere between half an hour to two hours, ranging from temperatures between 350 and 400 degrees.
The cooking time for a medium to a large loaf of meatloaf is about 1 hour and 15 minutes. Still, the answer to this question is not a clear-cut one, as it depends on a lot of factors.
The first and foremost factor is the type of meatloaf that you are cooking. For instance, if you are cooking a beef meatloaf, then it will take more time to cook than a chicken or turkey.
The second factor is also crucial. That is the temperature at which you are cooking your meatloaf. If you are using an oven, then it will take less time than if you are using a microwave or stovetop.
The third factor is the size of the loaf that you have made. The larger your loaf, the longer it will take to cook through and reach its desired temperature.
The fourth factor is whether or not your meatloaf has been pre-cooked before being placed in the loaf pan for baking. If so, then it will take less time to bake.
How Long Do You Cook A 1 Lb Meatloaf?
You should cook a 1 lb meatloaf for 20 to 30 min at 400 degrees, or 30 to 40 min at 350 degrees. Still, needless to say, the cooking time for a 1 lb meatloaf will depend on the type of meatloaf you are making.
For example, if you are making a traditional meatloaf, it will take about an hour to cook. If you are making a low-carb meatloaf, it will take about 45 minutes to cook.
Meatloaf is usually cooked at 350 degrees Fahrenheit for 45 minutes to one hour, depending on the size of the loaf and how well done you would like it to be.
How Long Do You Cook A 2 Lb Meatloaf?
If you are making a 2 lb meatloaf, then it will take about 45 to 50 minutes to cook in the oven at 350 degrees Fahrenheit and 35 to 45 min at 400 degrees. This is the perfect time and place for your meatloaf ingredients to perfectly mix together.
A lower temperature would lengthen the total time needed for cooking the meatloaf and would not allow the meat mixture to bake, making the meatloaf moist and undercooked.
Cooking meatloaf for the perfect amount of time is tricky. The cooking time varies depending on the size of the meatloaf and numerous other factors like temperature, thickness, and how much fat is in it.
How Long Do You Cook A 3 Lb Meatloaf?

Cook your meatloaf at 400 degrees for 45 to 55 minutes or around 1 hour at 350 degrees. The only thing you need to do is to make sure that the oven is preheated before putting the meatloaf in.
This will allow the classic meatloaf mixture to cure and reach the level of doneness to your personal preference.
The oven should be preheated at 350 degrees Fahrenheit, after which you can put the meatloaf in for about 45-60 minutes, depending on how done you want it to be.
How Long To Cook A 4 Lb Meatloaf?
You should cook a 4 lb meatloaf for at least one hour and a half at 350 degrees or for one hour at 400 degrees. A meatloaf can be cooked in a skillet, baking dish, casserole dish, or loaf pan.
A meatloaf should be browned on the top and bottom before it goes into the oven to ensure that it is fully cooked all the way through. You will also want to make sure that your meatloaf has enough room in your pan so that it doesn’t overflow while cooking.
Meatloaf is not the same as meatballs, meaning that you can use different mixes for making turkey meatloaf from frozen ground turkey as well.
How Long To Cook A 5 Lb Meatloaf?
The biggest meatloaf option will take at least 1 and a half hours to be done at 400 degrees and at least 2 and a half hours at 350 degrees.
Determining the cooking time for meatloaf is not a simple task because there are many factors that can affect cooking time.
The size of the meatloaf, the temperature of the oven, and whether or not you cover it with foil are just a few factors that can affect how long it takes to cook.
If you want to know how long it will take your meatloaf to cook, you should take into consideration all these factors. For example, if your oven is hotter than usual, then you will need to adjust your cooking time accordingly.
Meatloaf Finished Temperature: Internal Temperature For Cooked Meatloaf

The internal temperature for cooked meatloaf is 160 degrees Fahrenheit. You should also use a meat thermometer to make sure your meatloaf has reached an internal temperature of 160 degrees Fahrenheit. Use it before removing it from the oven.
This temperature is the same as the internal temperature for a steak. The success of your meatloaf depends on the ingredients you use and how you prepare it.
The best way to cook it is to bake it in an oven at 350 degrees Fahrenheit for about an hour. That is until the center reaches 160 degrees Fahrenheit of internal temp. Of course, don’t forget to use lean ground beef and follow a step-by-step guide.
That is why we have the best meatloaf recipe out there. The recommended cooking time for a medium-sized meatloaf is around 60 minutes. Use a digital thermometer to check the internal temperature of your meatloaf after 30 minutes of cooking.
Meatloaf Cooking Times And Temperatures Chart
Cooking meatloaf is an art form. It is a very versatile dish that can be prepared in many different ways. Some people have their own way of cooking it, but there are some common guidelines to follow when cooking this dish.
Degrees temp | Size of meatloaf | Meatloaf cook time |
---|---|---|
350 degrees Fahrenheit | 1 lb | 30 - 40 min |
2 lb | 45 - 50 min | |
3 lb | 1 hour - 1 hour and 15 min | |
4 lb | 1 hour and a half | |
5 lb | 2 hours | |
375 degrees Fahrenheit | 1 lb | 25 - 30 min |
2 lb | 40 - 45 min | |
3 lb | 1 hour | |
4 lb | 1 hour and a half | |
5 lb | 2 hours | |
400 degrees Fahrenheit | 1 lb | 20 - 30 min |
2 lb | 35 - 45 min | |
3 lb | 45 - 55 min | |
4 lb | 1 hour | |
5 lb | 1 hour 15 minutes |
Homemade Meatloaf Recipe: The Easy Way

Now that we know how long to cook meatloaf at 375 and every other temperature, get a large bowl and start preparing the best recipe for meatloaf. This recipe is a great way to use up leftovers and pair them with mashed potatoes.
This is perfect for a 2-pound meatloaf, and if you double the stats, you can get a 4-pound meatloaf. I am sure there will be no leftover meatloaf after you try out this delicious recipe for the first time:
Ingredients
• 1 pound lean ground beef
• 1/2 cup bread crumbs
• 1 egg
• 1/2 cup milk
• 1/2 cup ketchup
• 1/2 teaspoon salt
• 1/2 teaspoon Italian seasoning
• 1/2 teaspoon paprika powder
• 1/2 cup chopped onions
• 1/2 teaspoon garlic powder or onion powder
• 1/2 cup chopped bell pepper, green bell pepper, or other pepper
• 3 tablespoons black pepper
• 2 tablespoons brown sugar
• 2 tablespoons Worcestershire sauce
• 3 cloves garlic, minced or pressed through garlic press (optional)
Preparation:
In a large bowl, mix together the ground beef, bread crumbs, egg, milk, ketchup, salt, Italian seasoning, and paprika. In another bowl, mix all the vegetables in with the garlic (if using) and black pepper, brown sugar, and Worcestershire sauce and mix well.
Create a well in the center of your ingredients in order to create your meatloaf mixture. Now add 1/4 cup of the breadcrumbs and 3/4 cup of the vegetable mixture into the well. Mix those in with a spoon until all ingredients are combined.
Now form your meatloaf by hand and place it on a baking sheet lined with parchment paper. Form it into whatever shape you would like, and use your hands to shape it, so it will cook evenly.
How long to cook meatloaf at 375? Preheat oven to 375 degrees Fahrenheit, and for this 2-pound meatloaf, cook for up to 45 minutes.
Top with a side dish like perogies and sprinkle with parmesan. Let meatloaf rest at room temperature and inside of the baking sheet.
Know How Long To Bake Meatloaf At 375?
In conclusion, meatloaf is a dish that is popular in many countries. My family’s recipe calls for ground beef, pork, or lamb. You mix all the ingredients together and then bake the meat in an oven until it is cooked through.This is why I have guided you through the question of how long to cook meatloaf at 375. That is, so that you and your family can make meatloaf easily without it overcooking.
